#27 giver ikke en dadel for det...
Because of valerian's historical use as a sedative, anticonvulsant, migraine treatment and pain reliever, most basic science research has been directed at the interaction of valerian constituents with the GABA neurotransmitter receptor system. These studies remain inconclusive and all require independent replication. The mechanism of action of valerian in general, and as a mild sedative in particular, remains unknown. Valerian extracts appear to have some affinity for the GABAA receptor, a class of receptors on which benzodiazepines are known to act.[11][12]
Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A1 receptor sites.[13] This action likely does not contribute to the herb's sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this particular binding site. Hydrophilic extractions of the herb commonly sold over-the-counter, however, probably do not contain significant amounts of isovaltrate (according to the paper cited previously).