Just at little update.
I have isolatet the issue to the "TFRC 0" setting, beening for Dimm 0/2, the XMP profil want to use 110Ns but doing so will make the mobo hang and discard the setting.
Selecting 160Ns and keeping the rest of the XMP timings seems to be working, but i doubt they would set a bad timing in XMP like this and get away with it clean, so 110Ns should be useable by the mobo aswell, even if the issue is with the lower volt 🙂